Effects of Betulinic Acid and Ursolic Acid on IL-17-Induced CCL20 Release in Normal Human Epidermal Keratinocytes

Effects of Betulinic Acid and Ursolic Acid on IL-17-Induced CCL20 Release in Normal Human Epidermal Keratinocytes

Psoriasis is a chronic inflammatory skin disease characterized by erythema, infiltration, and scaling, which is mainly caused by interleukin (IL)-17. The use of molecular targeted drugs in specific therapies offers high efficacy; however, high medical costs and a significant risk of side effects hig...

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Main Authors: Anna Arai, Takahiro Oyama, Toyoaki Nakajima, Michiru Usui, Ena Sato, Takanori Kamiya, Midori Oyama, Takashi Tanikawa, Tomoharu Takeuchi, Takehiko Abe, Tomomi Hatanaka
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Life
Subjects:
psoriasis
epidermal keratinocyte
betulinic acid
ursolic acid
interleukin 17
C-C motif chemokine ligand 20
Online Access:https://www.mdpi.com/2075-1729/15/7/1073
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https://www.mdpi.com/2075-1729/15/7/1073

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