Prediction of miRNA-disease associations based on PCA and cascade forest

Abstract Background As a key non-coding RNA molecule, miRNA profoundly affects gene expression regulation and connects to the pathological processes of several kinds of human diseases. However, conventional experimental methods for validating miRNA-disease associations are laborious. Consequently, t...

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Bibliographic Details
Main Authors: Chuanlei Zhang, Yubo Li, Yinglun Dong, Wei Chen, Changqing Yu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Bioinformatics
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Online Access:https://doi.org/10.1186/s12859-024-05999-w
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