Generalizable design parameters for soluble T cell receptor-based T cell engagers

While most biological and cellular immunotherapies recognize extracellular targets, T cell receptor (TCR) therapeutics are unique in their ability to recognize the much larger pool of intracellular antigens found on virus-infected or cancerous cells. Recombinant T cell receptor (rTCR)-based therapeu...

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Bibliographic Details
Main Authors: Flora Huang, Arlene Sereno, Karen J Froning, Stephen J Demarest
Format: Article
Language:English
Published: BMJ Publishing Group 2022-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/3/e004281.full
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