Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders

Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders

Neurodevelopmental disorders (NDDs) affect 4.7% of the global population and are associated with delays in brain development and a spectrum of impairments that can lead to lifelong disability and even mortality. Identification of biomarkers for accurate diagnosis and medications for effective treatm...

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Bibliographic Details
Main Authors: Ziqin Yang, Nicole A. Teaney, Elizabeth D. Buttermore, Mustafa Sahin, Wardiya Afshar-Saber
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Neuroscience
Subjects:
hiPSC
neurodevelopmental disorders
patch clamping
MEA
voltage imaging
calcium imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1524577/full
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