Immune-mediated regeneration of cell-free vascular grafts in an ovine model

Immune-mediated regeneration of cell-free vascular grafts in an ovine model

Abstract We developed acellular tissue engineered vessels (ATEV) using small intestine submucosa (SIS) incorporating heparin and a novel protein named H2R5. ATEVs were implanted into the arterial circulation of an ovine animal model, demonstrating high primary patency rates over a period of three mo...

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Main Authors: Bita Nasiri, Arundhati Das, Karthik Ramachandran, Sai Harsha Bhamidipati, Yulun Wu, Shriramprasad Venkatesan, Rudiyanto Gunawan, Daniel D. Swartz, Stelios T. Andreadis
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-025-00400-7
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https://doi.org/10.1038/s41536-025-00400-7

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