miR-1, miR-133a, miR-29b and skeletal muscle fibrosis in chronic limb-threatening ischaemia
Abstract Chronic limb-threatening ischaemia (CLTI), the most severe manifestation of peripheral arterial disease (PAD), is associated with a poor prognosis and high amputation rates. Despite novel therapeutic approaches being investigated, no significant clinical benefits have been observed yet. Und...
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| Main Authors: | Alan J. Keane, Clara Sanz-Nogués, Dulan Jayasooriya, Michael Creane, Xizhe Chen, Caomhán J. Lyons, Isha Sikri, Katarzyna Goljanek-Whysall, Timothy O’Brien |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-76415-9 |
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