Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer

Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer

Abstract In attempt to discover novel aberrantly hypermethylated genes with putative tumor suppressor function in epithelial ovarian cancer (EOC), we applied expression profiling following pharmacologic inhibition of DNA methylation in EOC cell lines. Among the genes identified, one of particular in...

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Bibliographic Details
Main Authors: Pierre-Luc Mercier, Magdalena Bachvarova, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Karim Ghani, Bernard Têtu, Isabelle Bairati, Dimcho Bachvarov
Format: Article
Language:English
Published: Wiley 2011-10-01
Series:Molecular Oncology
Subjects:
Epithelial ovarian cancer
DNA methylation
DOK1
Tumor suppressor
Progression-free survival
DNA microarrays
Online Access:https://doi.org/10.1016/j.molonc.2011.07.003
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https://doi.org/10.1016/j.molonc.2011.07.003

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