Sesamin is an effective spleen tyrosine kinase inhibitor against IgE-mediated food allergy in computational, cell-based and animal studies

Food allergy has become a global concern. Spleen tyrosine kinase (SYK) inhibitors are promising therapeutics against allergic disorders. In this study, a total of 300 natural phenolic compounds were firstly subjected to virtual screening. Sesamin and its metabolites, sesamin monocatechol (SC-1) and...

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Bibliographic Details
Main Authors: Yu Li, Xuerui Chen, Longhua Xu, Xintong Tan, Dapeng Li, Dongxiao Sun-Waterhouse, Feng Li
Format: Article
Language:English
Published: Tsinghua University Press 2025-02-01
Series:Food Science and Human Wellness
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Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250081
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