Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection.

Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection.

<h4>Background</h4>Type III interferon, or interferon lambda (IFNλ) is a crucial antiviral cytokine induced by influenza infection. While IFNλ is important for anti-viral host defense, published data demonstrate that IFNλ is pathogenic during influenza/bacterial super-infection. It is kn...

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Main Authors: Helen E Rich, Danielle Antos, Collin C McCourt, Wen Quan Zheng, Louis J Devito, Kevin J McHugh, Radha Gopal, Jieru Wang, John F Alcorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0255309&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0255309&type=printable

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