The CRM1-dependent NES257−266 motif in the matrix protein: another factor influencing Newcastle disease virus propagation and virulence

The CRM1-dependent NES257−266 motif in the matrix protein: another factor influencing Newcastle disease virus propagation and virulence

Abstract As an important structural protein of Newcastle disease virus (NDV), the M protein plays a crucial role in the assembly and budding of the virus. In previous reports, we confirmed the existence of a classical nuclear export signal (NES) sequence on the M protein (i.e., amino acids 257 to 26...

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Bibliographic Details
Main Authors: Yaodong Zhang, Jun Dai, Lei Tan, Daoe Mu, Ziyan Zhang, Cuiping Song, Yang Qu, Ning Tang, Ying Liao, Chan Ding, Yingjie Sun, Xusheng Qiu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Veterinary Research
Subjects:
Newcastle disease virus
M protein
NES
CRM1
replication
virulence
Online Access:https://doi.org/10.1186/s13567-025-01552-6
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https://doi.org/10.1186/s13567-025-01552-6

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