Mechanisms and clinical translation of ICOS/ICOSL signaling pathway blockade in delaying vascular complications of type 2 diabetes
Abstract Background Type 2 diabetes mellitus (T2DM) is often complicated by vascular conditions such as atherosclerosis, which contribute significantly to morbidity and mortality. The ICOS/ICOSL signaling pathway has emerged as a promising target for mitigating these complications. This study aims t...
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| Main Authors: | Haiyan Zhang, LiBo Ruan, Xuemei Fu, Jinwen Yu, Qingrong Ruan, Yiyu Li, Hongying Wang, Heng Shao, Haoran Dong, Jianglan Cui |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | Diabetology & Metabolic Syndrome |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13098-025-01891-6 |
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