Peptidoglycan derived from Lacticaseibacillus rhamnosus and Lactobacillus acidophilus suppress TLR2/1-mediated inflammation in bovine endometrial epithelial cells

Peptidoglycan derived from Lacticaseibacillus rhamnosus and Lactobacillus acidophilus suppress TLR2/1-mediated inflammation in bovine endometrial epithelial cells

Bacteria and associated products are factors in the pathogenesis of bovine endometrial inflammation, contributing to reproductive dysfunction. While peptidoglycan derived from Staphylococcus aureus (PGN-Sa) has been demonstrated to induce pro-inflammatory responses and disrupt sperm–immune interacti...

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Bibliographic Details
Main Authors: Elham Waehama, Kenji Fukuda, Alireza Mansouri, Malinda Hulugalla, Ihshan Akthar, Mohamed Samy Yousef, Akio Miyamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
peptidoglycan
Lactobacillus species
Staphylococcus aureus
PAM3
inflammation
bovine endometrial epithelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1622307/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1622307/full

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