Bioinformatic analysis of molecular expression patterns during the development and progression of metabolic dysfunction-associated steatotic liver disease (MASLD)

Bioinformatic analysis of molecular expression patterns during the development and progression of metabolic dysfunction-associated steatotic liver disease (MASLD)

Abstract The global incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) continues to rise, primarily driven by the escalating obesity epidemic worldwide. MASLD, a spectrum of liver disorders, can progress to more severe conditions, metabolic dysfunction-associated steatohep...

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Bibliographic Details
Main Authors: Yuanfeng Lan, Ran Song, Duiping Feng, Junqi He
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Metabolic dysfunction-associated steatotic liver disease (MASLD)
Hepatocellular carcinoma (HCC)
Expression pattern cluster analysis
LASSO (least absolute shrinkage and selection operator)
Prognostic implications
Online Access:https://doi.org/10.1038/s41598-025-90744-3
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https://doi.org/10.1038/s41598-025-90744-3

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