Symptoms and adverse events in controlled human infection models

The potential and positioning of controlled human infection models (CHIMs) and human challenge trials (HCTs) in the investigation of infectious pathogens and efficacy of new anti-infectives or vaccines are under evaluation. CHIMs and HCTs can provide supporting data for decision-making in the develo...

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Bibliographic Details
Main Authors: Karen Götz, Poleta Luga, Jörg Rengel, Mei Masur, Marcela Juárez-Hernández, Isabelle Bekeredjian-Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1578560/full
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