Design and Biological Evaluation of hBest1-Containing Bilayer Nanostructures

Bestrophinopathies are a group of inherited retinal diseases caused by mutations in the <i>BEST1</i> gene. The protein encoded by this gene, bestorphin-1 (hBest1), is a calcium-dependent transmembrane channel localized on the basolateral membrane of retinal pigment epithelial (RPE) cells...

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Main Authors: Pavel Bakardzhiev, Teodora Koleva, Kirilka Mladenova, Pavel Videv, Veselina Moskova-Doumanova, Aleksander Forys, Sławomira Pusz, Tonya Andreeva, Svetla Petrova, Stanislav Rangelov, Jordan Doumanov
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/14/2948
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