Fatal acquired coagulation factor V deficiency after hepatectomy for advanced hepatocellular carcinoma as a possible immune checkpoint inhibitor-related adverse event: a case report

Fatal acquired coagulation factor V deficiency after hepatectomy for advanced hepatocellular carcinoma as a possible immune checkpoint inhibitor-related adverse event: a case report

Abstract Background Atezolizumab plus bevacizumab therapy was recently introduced as the first line for unresectable advanced hepatocellular carcinoma (HCC), but immune-related adverse events (IrAEs) due to atezolizumab are a great concern. Here, we report the case of a patient who developed fatal a...

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Main Authors: Shintaro Arakaki, Shinichiro Ono, Futoshi Kawamata, Shinichiro Ishino, Yasunori Uesato, Tomo Nakajima, Yukiko Nishi, Satoko Morishima, Shingo Arakaki, Tatsuji Maeshiro, Masayoshi Souri, Akitada Ichinose, Hiroaki Masuzaki, Mitsuhisa Takatsuki
Format: Article
Language:English
Published: Japan Surgical Society 2023-02-01
Series:Surgical Case Reports
Subjects:
Acquired coagulation factor deficiency
Hepatectomy
Immune checkpoint inhibitor-related adverse event
Online Access:https://doi.org/10.1186/s40792-023-01601-2
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https://doi.org/10.1186/s40792-023-01601-2

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