Antigenic and mutational insights into the Nipah virus G glycoprotein: implications for viral entry, host specificity, therapeutics, and vaccine development

Antigenic and mutational insights into the Nipah virus G glycoprotein: implications for viral entry, host specificity, therapeutics, and vaccine development

Nipah virus (NiV), a highly lethal RNA virus from the Paramyxoviridae family, causes severe neurological and respiratory diseases in humans. First identified during the 1990s outbreak in Malaysia, NiV remains a significant global health threat due to the absence of approved vaccines or antiviral tre...

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Bibliographic Details
Main Authors: Nur Syafiqah Mohamad Nasir, Yasmin Khairani Muhammad Ismadi, Noreafifah Semail, Wan Alif Syazwani Wan Alias, Nik Mohd Noor Nik Zuraina, Nik Yusnoraini Yusof, Zakuan Zainy Deris, Mohd Zulkifli Salleh
Format: Article
Language:English
Published: PeerJ Inc. 2025-08-01
Series:PeerJ
Subjects:
Antigenicity
Mutational analysis
Nipah virus
G glycoprotein
Viral entry
Host specificity
Online Access:https://peerj.com/articles/19835.pdf
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