Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies

Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies

BackgroundBelamcanda chinensis (L.) DC (Chinese name Shegan) has been widely used because of its pharmacological activity and remarkable therapeutic effects in sore throat. Tectorigenin, irigenin, and irisflorentin have been recognized as important quality indicators in Shegan. However, the metaboli...

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Bibliographic Details
Main Authors:	Jifeng Gu, Huishan Zhang, Mei Wang, Yuyang Zhou, Zhipeng Deng, Rong Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Pharmacology
Subjects:	tectorigenin irigenin irisflorentin atypical kinetics metabolism human liver microsomes
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1522857/full
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