Study of the effect of anxiolytic GML-1 on the activity of cytochrome CYP2C9 and CYP1A2 isoforms
Resume. Effects of GML-1 compound on activity of isoforms CYP2C9 and CYP1A2 of cytochrome P450 using marker drugs losartane and caffeine in experiments on rats were studied. GML-1 in a dose 10 mg/kg of 10 times higher than the maximum effective anxiolytic dose 1 mg / kg (intraperitoneal administrati...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC “Publisher OKI”
2019-02-01
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| Series: | Фармакокинетика и Фармакодинамика |
| Subjects: | |
| Online Access: | https://www.pharmacokinetica.ru/jour/article/view/92 |
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