Effectiveness of clopidogrel vs. ticagrelor based on the ABCD-GENE score in acute coronary syndrome patients following percutaneous coronary intervention

Effectiveness of clopidogrel vs. ticagrelor based on the ABCD-GENE score in acute coronary syndrome patients following percutaneous coronary intervention

AimThis study employs the ABCD-GENE score (age, body mass index, chronic kidney disease, diabetes, and CYP2C19 variants) to compare the effectiveness and safety of clopidogrel versus ticagrelor-based DAPT in ACS patients post-PCI.MethodsA total of consecutive 21,705 ACS patients who underwent PCI be...

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Main Authors: Xiaotong Xu, Kun Na, Miaohan Qiu, Xueqing Yang, Zizhao Qi, Jing Li, Kai Xu, Xiaozeng Wang, Yi Li, Yaling Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
CYP2C19 polymorphism
ABCD-GENE score
clopidogrel
ticagrelor
percutaneous coronary intervention
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1606327/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1606327/full

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