Circadian clock dysfunction in Parkinson’s disease: mechanisms, consequences, and therapeutic strategy
Abstract Parkinson’s Disease (PD) is a prevalent neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. This leads to hallmark motor features that include bradykinesia, resting tremor, rigidity, and postural instability, alongside with a ran...
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| Main Authors: | Müge Yalçin, Valentina Grande, Tiago Fleming Outeiro, Angela Relόgio |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | npj Parkinson's Disease |
| Online Access: | https://doi.org/10.1038/s41531-025-01009-9 |
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