Cholangiocarcinoma combined with biliary obstruction: an exosomal circRNA signature for diagnosis and early recurrence monitoring

Cholangiocarcinoma combined with biliary obstruction: an exosomal circRNA signature for diagnosis and early recurrence monitoring

Abstract Cholangiocarcinoma (CCA) is a highly malignant biliary tract cancer with currently suboptimal diagnostic and prognostic approaches. We present a novel system to monitor CCA using exosomal circular RNA (circRNA) via serum and biliary liquid biopsies. A pilot cohort consisting of patients wit...

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Main Authors: Ningyuan Wen, Dingzhong Peng, Xianze Xiong, Geng Liu, Guilin Nie, Yaoqun Wang, Jianrong Xu, Shaofeng Wang, Sishu Yang, Yuan Tian, Bei Li, Jiong Lu, Nansheng Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2024-05-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-01814-3
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https://doi.org/10.1038/s41392-024-01814-3

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