Andrographolide Inhibits Nuclear Factor-κB Activation through JNK-Akt-p65 Signaling Cascade in Tumor Necrosis Factor-α-Stimulated Vascular Smooth Muscle Cells

Critical vascular inflammation leads to vascular dysfunction and cardiovascular diseases, including abdominal aortic aneurysms, hypertension, and atherosclerosis. Andrographolide is the most active and critical constituent isolated from the leaves of Andrographis paniculata, a herbal medicine widely...

Full description

Saved in:
Bibliographic Details
Main Authors: Yu-Ying Chen, Ming-Jen Hsu, Cheng-Ying Hsieh, Lin-Wen Lee, Zhih-Cherng Chen, Joen-Rong Sheu
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/130381
Tags: Add Tag
No Tags, Be the first to tag this record!