Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion

Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion

Abstract Cardiosphere‐derived cells (CDCs) reduce myocardial infarct size via secreted extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage polarization. We questioned whether short non‐coding RNA species of unknown function within CDC‐EVs contribute to cardioprotection. The...

Full description

Saved in:
Bibliographic Details
Main Authors: Linda Cambier, Geoffrey de Couto, Ahmed Ibrahim, Antonio K Echavez, Jackelyn Valle, Weixin Liu, Michelle Kreke, Rachel R Smith, Linda Marbán, Eduardo Marbán
Format: Article
Language:English
Published: Springer Nature 2017-02-01
Series:EMBO Molecular Medicine
Subjects:
extracellular vesicle
macrophage
RNA
stem cells
Online Access:https://doi.org/10.15252/emmm.201606924
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.15252/emmm.201606924

Similar Items