CSF Amyloid-β42 associates with neuropsychiatric and cognitive outcomes via cerebral glucose metabolism

CSF Amyloid-β42 associates with neuropsychiatric and cognitive outcomes via cerebral glucose metabolism

Abstract Amyloid-β42 (Aβ42) regulates synaptic plasticity and memory formation at physiological levels in the brain, but in Alzheimer’s disease (AD), it can disrupt brain function and glucose metabolism. This disruption contributes to cognitive decline and neuropsychiatric symptoms, highlighting the...

Full description

Saved in:
Bibliographic Details
Main Authors: Ali Azargoonjahromi, Hamide Nasiri, for the Alzheimer’s Disease Neuroimaging Initiative#
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Brain
Subjects:
Amyloid-β42
Cerebral glucose metabolism
Neuropsychiatric symptoms
Cognitive performance
Mild cognitive impairment
Alzheimer’s disease
Online Access:https://doi.org/10.1186/s13041-025-01229-3
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13041-025-01229-3

Similar Items