A simple method for non-denaturing purification of biotin-tagged proteins through competitive elution with free biotin

The use of avidin or streptavidin in the purification of biotinylated proteins has been highly restricted due to the harsh and denaturing elution conditions. Here, we use biotinylated bovine serum albumin as a working model to demonstrate a simple and rapid method for biotin-tagged protein purificat...

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Bibliographic Details
Main Authors: Kui Lin, Qin Yan, Audrey Mitchell, Natasha Funk, Catherlin Lu, Hao Xiao
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:BioTechniques
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Online Access:https://www.future-science.com/doi/10.2144/btn-2019-0088
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