SLC4A10 impedes atherosclerosis by diminishing IFN-γ/GZMB levels of CD8+ T cells via the MAPK pathway

SLC4A10 impedes atherosclerosis by diminishing IFN-γ/GZMB levels of CD8+ T cells via the MAPK pathway

Background and aimsCD8+ T cell subpopulations participate in the formation of atherosclerotic plaques through activation or exhaustion. Yet, it is unclear which specific subset it critically involved. The SLC4A10+ CD8+ T cell possess atherogenic attributes and this study aimed to investigate the ass...

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Bibliographic Details
Main Authors: Bo Chen, Lei Zhu, Xueguang Lin, Kristine J. S. Kwan, Jie Wang, Yijie Lu, Jialong Li, Ying Deng, Shuai Jiang, Jingdong Tang, Bo Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
plaque stability
CD8+ T cells
SLC4A10
MAPK pathway
atherosclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1568999/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1568999/full

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