A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus
Abstract Hydrocephalus, whether arising from post-hemorrhagic or post-traumatic origins, poses significant challenges in clinical management. Lumboperitoneal shunting (LPS) emerges as a viable therapeutic intervention, yet comparative analyses between these etiologies remain scarce. This retrospecti...
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2025-01-01
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| author | Tong Sun Siyang Chen Junjie Wang Chao You Ke Wu |
| author_facet | Tong Sun Siyang Chen Junjie Wang Chao You Ke Wu |
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| description | Abstract Hydrocephalus, whether arising from post-hemorrhagic or post-traumatic origins, poses significant challenges in clinical management. Lumboperitoneal shunting (LPS) emerges as a viable therapeutic intervention, yet comparative analyses between these etiologies remain scarce. This retrospective study aims to compare the efficacy and safety of LPS placement in patients with post-hemorrhagic (PHH) and post-traumatic hydrocephalus (PTH). This retrospective study investigates shunting outcomes in patients aged 18 years or older diagnosed with PHH or PTH who underwent LPS between 2014 and 2018. Primary outcomes included shunt reoperation rates, with secondary outcomes encompassing modified Rankin Scale (mRS) and National Institute of Health Stroke Scale (NIHSS) scores, Evans index, complications, and length of hospital stay. Favorable outcomes were defined as an mRS score of 2 or less. A total of 34 PHH and 48 PTH patients were included, with baseline characteristics being similar between groups. Shunt reoperation rates were comparable between PHH (23.5%) and PTH (27.1%) groups (P = 0.716). At 2 years, favorable outcomes were observed in 82.4% of PHH patients and 72.9% of PTH patients (P = 0.318). NIHSS scores at discharge (P = 0.230) and at 2 years (P = 0.530) showed no significant differences. However, PHH patients exhibited shorter hospital stays post-LPS implantation (P = 0.025). LPS placement demonstrates comparable outcomes in patients with PHH and PTH, with similar rates of shunt reoperation and complications, as well as equivalent neurological outcomes. However, Notably, PTH patients exhibited a higher risk of shunt malfunction compared to PHH patients, along with prolonged hospital stays post-LPS implantation. |
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| institution | Kabale University |
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| spelling | doaj-art-151ddc41e1fe446dbf36f4ec40641ac22025-01-05T12:20:41ZengNature PortfolioScientific Reports2045-23222025-01-011511810.1038/s41598-024-84158-wA comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalusTong Sun0Siyang Chen1Junjie Wang2Chao You3Ke Wu4Department of Neurosurgery, West China Hospital, Sichuan UniversityHealth Management Center, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Neurosurgery, West China Hospital, Sichuan UniversityDepartment of Neurosurgery, West China Hospital, Sichuan UniversityDepartment of Neurosurgery, Xichang Peoples’ HospitalAbstract Hydrocephalus, whether arising from post-hemorrhagic or post-traumatic origins, poses significant challenges in clinical management. Lumboperitoneal shunting (LPS) emerges as a viable therapeutic intervention, yet comparative analyses between these etiologies remain scarce. This retrospective study aims to compare the efficacy and safety of LPS placement in patients with post-hemorrhagic (PHH) and post-traumatic hydrocephalus (PTH). This retrospective study investigates shunting outcomes in patients aged 18 years or older diagnosed with PHH or PTH who underwent LPS between 2014 and 2018. Primary outcomes included shunt reoperation rates, with secondary outcomes encompassing modified Rankin Scale (mRS) and National Institute of Health Stroke Scale (NIHSS) scores, Evans index, complications, and length of hospital stay. Favorable outcomes were defined as an mRS score of 2 or less. A total of 34 PHH and 48 PTH patients were included, with baseline characteristics being similar between groups. Shunt reoperation rates were comparable between PHH (23.5%) and PTH (27.1%) groups (P = 0.716). At 2 years, favorable outcomes were observed in 82.4% of PHH patients and 72.9% of PTH patients (P = 0.318). NIHSS scores at discharge (P = 0.230) and at 2 years (P = 0.530) showed no significant differences. However, PHH patients exhibited shorter hospital stays post-LPS implantation (P = 0.025). LPS placement demonstrates comparable outcomes in patients with PHH and PTH, with similar rates of shunt reoperation and complications, as well as equivalent neurological outcomes. However, Notably, PTH patients exhibited a higher risk of shunt malfunction compared to PHH patients, along with prolonged hospital stays post-LPS implantation.https://doi.org/10.1038/s41598-024-84158-wCerebrospinal fluid shuntLumboperitoneal shuntHydrocephalusTraumatic brain injuryHemorrhagic stroke |
| spellingShingle | Tong Sun Siyang Chen Junjie Wang Chao You Ke Wu A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus Scientific Reports Cerebrospinal fluid shunt Lumboperitoneal shunt Hydrocephalus Traumatic brain injury Hemorrhagic stroke |
| title | A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus |
| title_full | A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus |
| title_fullStr | A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus |
| title_full_unstemmed | A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus |
| title_short | A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus |
| title_sort | comparative analysis of lumboperitoneal shunt outcomes in patients with post hemorrhagic and post traumatic hydrocephalus |
| topic | Cerebrospinal fluid shunt Lumboperitoneal shunt Hydrocephalus Traumatic brain injury Hemorrhagic stroke |
| url | https://doi.org/10.1038/s41598-024-84158-w |
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