Boosted high-throughput D⁺ transfer from D₂O to unsaturated bonds via Pdδ+ cathode for solvent-free deuteration

Abstract Deuterated organic compounds have gained significant attention due to their diverse applications, including reaction mechanism studies, probes for metabolism and pharmacokinetics, and raw materials for labeled compounds and polymers. Conventional reductive deuteration methods are limited by...

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Bibliographic Details
Main Authors: Xiu-Feng Zhang, Shi-Nan Zhang, Zhao Zhang, Bing-Liang Leng, Kai-Yuan Lu, Jie-Sheng Chen, Xin-Hao Li
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59776-1
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