Lymphocyte Inhibition Mechanisms and Immune Checkpoints in COVID-19: Insights into Prognostic Markers and Disease Severity

Lymphocyte Inhibition Mechanisms and Immune Checkpoints in COVID-19: Insights into Prognostic Markers and Disease Severity

<i>Background and Objectives</i>: Immune checkpoint inhibitors such as PD-1 and TIM-3 play an important role in regulating the host immune response and are proposed as potential prognostic markers and therapeutic targets in severe cases of COVID-19. We evaluated the expression of PD-1 an...

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Bibliographic Details
Main Authors: Martina Schniederova, Anna Bobcakova, Marian Grendar, Adam Markocsy, Andrej Ceres, Michal Cibulka, Dusan Dobrota, Milos Jesenak
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Medicina
Subjects:
immune checkpoint inhibitors
immune predictors
COVID-19
machine-learning algorithm
Online Access:https://www.mdpi.com/1648-9144/61/2/189
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