Epigenetic silencing and genome dynamics determine the fate of giant virus endogenizations in Acanthamoeba

Abstract Background Endogenized giant viruses are emerging as major contributors to the genome evolution of microbial eukaryotes, with both degraded and fully functional latent viruses being found integrated in diverse lineages. The mechanisms that determine the fate of viral integrants are poorly u...

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Bibliographic Details
Main Authors: Cédric Blais, Morgan J. Colp, Luke A. Sarre, Alex de Mendoza, John M. Archibald
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-025-02280-1
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