The Causal Relationship between Inflammatory Cytokines and Liver Cirrhosis in European Descent: A Bidirectional Two-Sample Mendelian Randomization Study and the First Conclusions

The Causal Relationship between Inflammatory Cytokines and Liver Cirrhosis in European Descent: A Bidirectional Two-Sample Mendelian Randomization Study and the First Conclusions

Background: Observational studies have highlighted the pivotal role of inflammatory cytokines in cirrhosis progression. However, the existence of a causal link between inflammatory cytokines and cirrhosis remains uncertain. In this study, we conducted a bidirectional Mendelian randomization (MR) ana...

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Main Authors: Shiya Shi, Yanjie Zhou, He Zhang, Yalan Zhu, Pengjun Jiang, Chengxia Xie, Tianyu Feng, Yuping Zeng, He He, Yao Luo, Jie Chen
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomedicines
Subjects:
inflammatory cytokines
liver cirrhosis
mendelian randomization study
Online Access:https://www.mdpi.com/2227-9059/12/10/2264
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