An in vivo “turning model” reveals new RanBP9 interactions in lung macrophages

An in vivo “turning model” reveals new RanBP9 interactions in lung macrophages

Abstract The biological functions of the scaffold protein Ran Binding Protein 9 (RanBP9) remain elusive in macrophages or any other cell type where this protein is expressed together with its CTLH (C-terminal to LisH) complex partners. We have engineered a new mouse model, named RanBP9-TurnX, where...

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Main Authors: Yasuko Kajimura, Shuxin Dong, Anna Tessari, Arturo Orlacchio, Alexandra Thoms, Maria Concetta Cufaro, Federica Di Marco, Foued Amari, Min Chen, Shimaa H. A. Soliman, Lara Rizzotto, Liwen Zhang, Damu Sunilkumar, Joseph M. Amann, David P. Carbone, Amer Ahmed, Giuseppe Fiermonte, Mike A. Freitas, Alessia Lodi, Piero Del Boccio, Lino Tessarollo, Dario Palmieri, Vincenzo Coppola
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02456-2
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https://doi.org/10.1038/s41420-025-02456-2

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