Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy

Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy

Background: Adult B-cell acute lymphoblastic leukaemia (aB-ALL) is characterised by abnormal differentiation and proliferation of lymphoid progenitors. Despite a significant improvement in relapse-free and overall survival for children with B-ALL, aB-ALL has a particularly poor prognosis with a 5-ye...

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Bibliographic Details
Main Authors: Eithar Mohamed, Sara Goodman, Leah Cooksey, Daniel M. Fletcher, Olivia Dean, Viktoriya B. Boncheva, Ken I. Mills, Kim H. Orchard, Barbara-ann Guinn
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Onco
Subjects:
adult B-cell acute lymphocytic leukaemia
antigen discovery
cancer vaccines
SMAD3
TEAD4
immunotherapy
Online Access:https://www.mdpi.com/2673-7523/5/2/19
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https://www.mdpi.com/2673-7523/5/2/19

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