Lonicerin attenuates high-fat diet-induced hepatic steatosis through modulation of the gut microbiota-bile acid-FXR axis in mice

Lonicerin attenuates high-fat diet-induced hepatic steatosis through modulation of the gut microbiota-bile acid-FXR axis in mice

Lonicera japonica Thunb. is widely used in Asian countries as a food ingredient to make healthy drinks, with lonicerin, a flavone O-glycoside, as a predominant bioactive compound. This study investigated lonicerin’s effects on high-fat diet-induced hepatic steatosis in mice, compared to its aglycone...

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Bibliographic Details
Main Authors: Shuang Wang, Chunyue Zhao, Xueran Huang, Yongfen Gao, Yang Qiu, Rui Jiao, Hanyue Zhu, Huafang Ding, Rui Lin, Zouyan He
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Functional Foods
Subjects:
Lonicerin
Luteolin
Hepatic steatosis
Gut microbiota
Bile acid
Farnesoid X receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624004687
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http://www.sciencedirect.com/science/article/pii/S1756464624004687

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