Analysis of Recombinant Protein Expression by MALDI-TOF Mass Spectrometry of Bacterial Colonies

E. coli expressing soluble recombinant HIV antigens were analyzed directly by MALDI-TOF mass spectrometry (MS) from bacterial colonies picked from agar plates. An HIV envelope (ENV) antigen construct, penvA, was expressed in E. coli by transformation of the plasmid pPL/penvA-M. The plasmid was co-tr...

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Bibliographic Details
Main Authors: Martin A. Winkler, Robert K. Hickman, Alan Golden, Hoda Aboleneen
Format: Article
Language:English
Published: Taylor & Francis Group 2000-05-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/00285st01
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