Resistance signatures to oncolytic vesiculoviruses in pancreatic ductal adenocarcinoma

Resistance signatures to oncolytic vesiculoviruses in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) shows limited response to conventional therapies and immunotherapy due to dense stromal barriers and poor immunogenicity. Oncolytic vesiculoviruses hold therapeutic potential for PDAC by lysis of PDAC cells to release tumor-associated antigens, increasing tumo...

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Main Authors: Chelsae R. Watters, Oumar Barro, Musa Gabere, Mia Y. Masuda, Natalie M. Elliott, Elizabeth A. Raupach, Khandoker Usran Ferdous, Mulu Z. Tesfay, Omeed Moaven, Yumei Zhou, Michael T. Barrett, Kenneth H. Buetow, Bolni Marius Nagalo, Mitesh J. Borad
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Molecular Therapy: Oncology
Subjects:
MT
Regular Issue
oncolytics
vesiculovirus
resistance
pancreatic cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2950329925000062
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http://www.sciencedirect.com/science/article/pii/S2950329925000062

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