Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes.

Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes.

Macrophages exhibit diverse effector phenotypes depending on the stimuli and their microenvironment. Classically activated macrophages are primed with interferon (IFN)γ and stimulated with pathogen-associated molecular patterns. They produce inflammatory mediators and inflammatory cytokines, such as...

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Main Authors: Wipawee Wongchana, Pornrat Kongkavitoon, Pattarin Tangtanatakul, Chutamath Sittplangkoon, Patcharavadee Butta, Supatta Chawalitpong, Thitiporn Pattarakankul, Barbara A Osborne, Tanapat Palaga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198609/1/pone.0198609.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210218%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210218T052842Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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