Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly

Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly

IntroductionHippocampal volume loss occurs physiologically with age, but an accelerated rate of volume loss is linked to neurodegenerative diseases. While evidence suggests that cross-sectional study designs tend to underestimate hippocampal atrophy rates compared to longitudinal approaches, few stu...

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Main Authors: Vivian Schultz, Benita Schmitz-Koep, Aurore Menegaux, Melissa Thalhammer, Severin Schramm, Su Hwan Kim, Claus Zimmer, Christian Sorg, Panteleimon Giannakopoulos, Marie-Louise Montandon, François R. Herrmann, Cristelle Rodriguez, Sven Haller, Dennis M. Hedderich
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
brain
MRI
hippocampus
atrophy
neurodegeneration
aging
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1542857/full
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https://www.frontiersin.org/articles/10.3389/fnagi.2025.1542857/full

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