Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?

Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?

<h4>Introduction</h4>C-reactive protein (CRP) levels are associated with cardiovascular disease and systemic inflammation. We assessed whether CRP-associated loci were associated with serum CRP and retinal markers of microvascular disease, in Asian populations.<h4>Methods</h4>...

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Main Authors: Rajkumar Dorajoo, Ruoying Li, Mohammad Kamran Ikram, Jianjun Liu, Philippe Froguel, Jeannette Lee, Xueling Sim, Rick Twee-Hee Ong, Wan Ting Tay, Chen Peng, Terri L Young, Alexandra I F Blakemore, Ching Yu Cheng, Tin Aung, Paul Mitchell, Jie Jin Wang, Caroline C Klaver, Eric Boerwinkle, Ronald Klein, David S Siscovick, Richard A Jensen, Vilmundur Gudnason, Albert Vernon Smith, Yik Ying Teo, Tien Yin Wong, E-Shyong Tai, Chew-Kiat Heng, Yechiel Friedlander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0067650&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0067650&type=printable

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