Circular RNA signature of aggressive CLL with t(14;19)(q32;q13). An ERIC study

Circular RNA signature of aggressive CLL with t(14;19)(q32;q13). An ERIC study

Abstract In Chronic Lymphocytic Leukemia (CLL), t(14;19)(q32;q13), leading to the overexpression of BCL3, is found in ∼1% of cases and is associated with an aggressive disease. In this study, leveraging a large CLL patient cohort collected thanks to an international collaboration, we investigate for...

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Main Authors: Eleonora Roncaglia, Enrico Gaffo, Giulia Calabretto, Moritz Fürstenau, Kerry A. Rogers, Panagiotis Baliakas, Chenghua Cui, Cecelia Miller, Claudia Haferlach, Karla Plevova, David Oscier, Zadie Davis, Florence Nguyen-Khac, Gian Matteo Rigolin, Anastasia Athanasiadou, Fanny Baran-Marszak, Alberto Valiente, Maria José Terol, Pau Abrisqueta, Blanca Espinet, Anna Puiggros, Annalisa Martines, Laura Bonaldi, Francesca Romana Mauro, Lydia Scarfò, Thomas Chatzikonstantinou, Eugen Tausch, Karl-Anton Kreuzer, Arnon Kater, Francesc Bosch, Michael Doubek, Panagiotis Panagiotidis, Olga Kalashnikova, Federica Frezzato, Valeria Ruocco, Silvia Orsi, Kimia Salek, Roberto Merlo, Alberto Caregari, Ilias Glogovitis, Alessandro Cellini, Francesco Angotzi, Andrea Serafin, Shuhua Yi, Barbara Eichhorst, Jennifer A. Woyach, Antonio Cuneo, Paolo Ghia, Kostas Stamatopoulos, Livio Trentin, Andrea Visentin, Stefania Bortoluzzi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Hematology & Oncology
Subjects:
CLL
T(14;19)
Circular RNA
BCL3
Online Access:https://doi.org/10.1186/s13045-025-01725-y
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https://doi.org/10.1186/s13045-025-01725-y

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