Repurposing pinaverium bromide against Staphylococcus and its biofilms with new mechanisms

Repurposing pinaverium bromide against Staphylococcus and its biofilms with new mechanisms

Abstract Antibiotic resistance by methicillin-resistant Staphylococcus aureus (MRSA) is an urgent threat to human health. The biofilm and persister cells formation ability of MRSA and Staphylococcus epidermidis often companied with extremely high antimicrobial resistance. Pinaverium bromide (PVB) is...

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Bibliographic Details
Main Authors: She Pengfei, Yang Yifan, Liu Shasha, Guo Shaowei, Huan Guanqing, Xiao Dan, Wu Yong
Format: Article
Language:English
Published: SpringerOpen 2024-12-01
Series:AMB Express
Subjects:
Staphylococcus
Biofilm
Persister
Drug repurposing
Proton motive force
Online Access:https://doi.org/10.1186/s13568-024-01809-x
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https://doi.org/10.1186/s13568-024-01809-x

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