Dynamic human liver proteome atlas reveals functional insights into disease pathways

Dynamic human liver proteome atlas reveals functional insights into disease pathways

Abstract Deeper understanding of liver pathophysiology would benefit from a comprehensive quantitative proteome resource at cell type resolution to predict outcome and design therapy. Here, we quantify more than 150,000 sequence‐unique peptides aggregated into 10,000 proteins across total liver, the...

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Main Authors: Lili Niu, Philipp E Geyer, Rajat Gupta, Alberto Santos, Florian Meier, Sophia Doll, Nicolai J Wewer Albrechtsen, Sabine Klein, Cristina Ortiz, Frank E Uschner, Robert Schierwagen, Jonel Trebicka, Matthias Mann
Format: Article
Language:English
Published: Springer Nature 2022-05-01
Series:Molecular Systems Biology
Subjects:
clinical proteomics
liver disease
liver fibrosis
MS‐based proteomics
tissue proteome atlas
Online Access:https://doi.org/10.15252/msb.202210947
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https://doi.org/10.15252/msb.202210947

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