The importance of targeted next-generation sequencing based genomic profiling in the diagnosis of childhood acute myeloid leukemia: a single center experience

The importance of targeted next-generation sequencing based genomic profiling in the diagnosis of childhood acute myeloid leukemia: a single center experience

Background. The management of pediatric acute myeloid leukemia (AML) is based on the prognostic risk classification of initial leukemia. Targeted next-generation sequencing (NGS) is a reliable method used to identify recurrently mutated genes of pediatric AML and associated prognosis. Methods. In...

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Main Authors: Dilek Kaçar, Büşranur Çavdarlı, Ayça Koca Yozgat, Melek Işık, Fatma Burçin Kurtipek, Fatma Tuba Yıldırım, Turan Bayhan, Dilek Gürlek Gökçebay, Namık Yaşar Özbek, Neşe Yaralı
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2024-12-01
Series:The Turkish Journal of Pediatrics
Subjects:
acute myeloid leukemia
children
mutation
next-generation sequencing
Online Access:https://turkjpediatr.org/article/view/4699
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https://turkjpediatr.org/article/view/4699

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