REST/NRSF Preserves muscle stem cell identity by repressing alternate cell fate

REST/NRSF Preserves muscle stem cell identity by repressing alternate cell fate

Abstract Cell fate and identity require timely activation of lineage-specific and concomitant repression of alternate-lineage genes. How this process is epigenetically encoded remains largely unknown. In skeletal muscle stem cells, the myogenic regulatory factors are well-established drivers of musc...

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Main Authors: Korin Sahinyan, Darren M. Blackburn, Marie-Michelle Simon, Felicia Lazure, Tony Kwan, David H. Wilson, Maryam Vahidyeganeh, Nawal Alsadi, Julia von Maltzahn, Yasuhiro Yamada, Arezu Jahani-Asl, Guillaume Bourque, Michael A. Rudnicki, Vahab D. Soleimani
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62758-y
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https://doi.org/10.1038/s41467-025-62758-y

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