Restoring immune tolerance in pre-RA: immunometabolic dialogue between gut microbiota and regulatory T cells

Restoring immune tolerance in pre-RA: immunometabolic dialogue between gut microbiota and regulatory T cells

Rheumatoid arthritis (RA) is a complex chronic autoimmune disease that remains incurable for most patients. With advances in our understanding of the disease’s natural history, the concept of pre-RA has emerged as a window of opportunity to intervene before irreversible joint damage occurs. Numerous...

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Bibliographic Details
Main Authors: Anqi Gao, Ruihe Wu, Yanfei Mu, Ruqing Jin, Saixin Jiang, Chong Gao, Xiaofeng Li, Caihong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
pre-RA
regulatory T cell
gut microbiota
immunometabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1565133/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1565133/full

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