Hippocampal neuroinflammation and neuronal injury in the acute phase of pentylenetetrazol induced epilepsy mouse model

Hippocampal neuroinflammation and neuronal injury in the acute phase of pentylenetetrazol induced epilepsy mouse model

ObjectiveTo investigate the activation of microglia and astrocytes, the secretion of pro-inflammatory factors, and the survival of neurons in the hippocampus of mice with acute seizures induced by pentylenetetrazol (PTZ) 24 hours after the onset of seizures. MethodsAdult male C57BL/6 mice were rando...

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Bibliographic Details
Main Authors: Linyu ZHI, Wanruo HAN, WANG Benjamin Hongye, Guoxiang WANG, Xu LIU
Format: Article
Language:English
Published: Shanghai Chinese Clinical Medicine Press Co., Ltd. 2025-04-01
Series:Zhongguo Linchuang Yixue
Subjects:
epilepsy
hippocampal neurons
neuroinflammation
microglia
Online Access:https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2024.20241305
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https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2024.20241305

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