Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression?

Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression?

BackgroundChronic HCV (CHC) infection is associated with autoimmunity. IgG autoantibodies to apolipoprotein A-I (AAA-I) predict all-cause mortality. We evaluated AAA-I in CHC patients and in those who were not viraemic, either because of spontaneous resolution (SR) of infection or HCV clearance foll...

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Main Authors: Simon H. Bridge, Sabrina Pagano, John K. Lodge, Isaac T. Shawa, Paula Marin-Crespo, Matthew E. Cramp, David A. Sheridan, Simon D. Taylor-Robinson, Nicolas Vuilleumier, R. Dermot G. Neely, Margaret F. Bassendine
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
hepatitis C virus (HCV)
autoantibodies
apolipoprotein A-I
disease progression
cirrhosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1461041/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1461041/full

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