Repair-associated macrophages increase after early-phase microglia attenuation to promote ischemic stroke recovery

Repair-associated macrophages increase after early-phase microglia attenuation to promote ischemic stroke recovery

Abstract Ischemic stroke recovery involves dynamic interactions between the central nervous system and infiltrating immune cells. Peripheral immune cells compete with resident microglia for spatial niches in the brain, but how modulating this balance affects recovery remains unclear. Here, we use PL...

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Main Authors: Xiaotao Zhang, Huaming Li, Yichen Gu, An Ping, Jiarui Chen, Qia Zhang, Zhouhan Xu, Junjie Wang, Shenjie Tang, Rui Wang, Jianan Lu, Lingxiao Lu, Chenghao Jin, Ziyang Jin, Jianmin Zhang, Ligen Shi
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58254-y
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https://doi.org/10.1038/s41467-025-58254-y

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