Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradiation via m6A modification

Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradiation via m6A modification

Abstract With advancements in radiotherapy technologies, the detrimental effects of ionizing radiation on biological systems, particularly the hematopoietic system, have caused significant concern. N6-methyladenosine (m6A), the most pervasive representative of post-transcriptional modifications, pla...

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Bibliographic Details
Main Authors: Shuqin Zhang, Yajia Cheng, Yujia Gao, Feifei Xu, Yuna Wang, Junling Zhang, Yue Shang, Deguan Li, Saijun Fan
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Molecular Biomedicine
Subjects:
Radiation injury
RNA methylation
Small nucleolar RNA host gene 15 (Snhg15)
Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)
Hematopoiesis
Online Access:https://doi.org/10.1186/s43556-025-00279-2
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https://doi.org/10.1186/s43556-025-00279-2

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